COVID-19 and its relationship with ischemic cardiovascular disease. systematic review of literature and meta-analysis.
COVID-19 y su relación con la enfermedad cardiovascular isquémica Systematic Review and Meta-analysis
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The COVID-19 pandemic had a significant impact on all health indicators related to people's quality of life, demonstrating effects not only at the time of infection but also significant sequelae up to 90 days after the onset of symptoms. Objective: To determine the association of COVID-19 with ischemic cerebrovascular disease in adults. Method: A systematic review of the literature with meta-analysis was developed based on the search for scientific evidence in the Pubmed, Clinical Key, Elsevier, Access medicine, and Ovid databases to identify relevant studies that met the inclusion and exclusion criteria in 2023. Cross-sectional, longitudinal, or cohort studies were selected, without language or time limitations, that showed the association of COVID-19 with the development of ischemic cerebrovascular disease, cerebrovascular accident, or STROKE. Results: Articles published between 2020 and 2023 were analyzed, including cohort and case-control studies. The association between the development of stroke associated with COVID-19 was found to be statistically significant (OR 1.34, 95% CI 1.27–1.42). Conclusions: The comparison of the data allows us to demonstrate that COVID-19 not only had an effect on the respiratory and musculoskeletal systems, but also had a more severe effect on the neurological system than previously thought.
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